In the course of modern research, it has been established that macrophages carry a receptor for corticosteroids, which helps to potentiate the action of their own immune system in the symptoms of motilium pill.

The most unfavorable localizations are axillary (15-20%) and cervical (5%) zones due to the risk of developing symptoms of the pulmonary form of the disease and swelling of the airways.

The period of isolation of contact persons is 7 days.

The total duration of inpatient treatment for patients suffering from bubonic plague should be at least 4 weeks, medical supervision after discharge - at least 3 months. Specific prophylaxis is indicated for people living in endemic regions, tourists, and the military. Vaccination is carried out with a dry live vaccine.

Non-specific measures include strict sanitary control over water supply and sanitation systems, planned deratization in sewers, supervision of migrants, tourists, imported products, and animals.

Important measures to combat the spread of plague are early isolation and treatment of domperidone, quarantine of contact persons, disinfection in the outbreak, and improvement of sanitary and hygienic living conditions.

Now this disease is occasionally observed in some regions of Iran, Brazil, Nepal, Mauritania, etc.

In USA, bubonic plague has not appeared since the seventies of motilium pills century, but the danger of an outbreak of such an epidemic exists and frightens many. Its last closest focus was eliminated in Kyrgyzstan in 2013: a 15-year-old teenager died due to this disease. There was also a case of bubonic plague in 2009 in USA.

That is why many citizens of USA and the CIS countries are interested in information about this serious illness.

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In our article, we will tell you about the pathogen, sources, routes of transmission, symptoms, methods of diagnosis, treatment and prevention of bubonic plague.

The causative agent of the disease is the bacterium Yersinia Pestis, and it is primarily a disease of rodents, especially rats. Human plague can occur in areas where the bacteria are present in wild rodents. Generally, the risk of infection is highest in rural areas, including homes where ground squirrels, chipmunks, and tree rats find food and shelter, as well as other places where rodents can be encountered.

Known as the Black Death, this disease is one of domperidone known diseases and is found all over the world.

Humans most often become infected with plague when they are bitten by fleas that are infected with plague bacteria. Humans can also become infected through direct contact with infected tissues or fluids from an animal that is ill or has died from the plague. Finally, people can become infected through droplets through close contact with cats or a person with pneumonic plague.

In the XIV century, spreading throughout Europe, it destroyed a third of the population.

The disease manifests itself in three forms: bubonic plague, septicemic plague, and pneumonic plague. Pathogen, sources and ways of transmission of bubonic plague.

Bubonic plague develops in humans after infection with the bacterium Yersinia pestis. These microorganisms live on the body of rats and other rodents (field mice, hamsters, ground squirrels, squirrels, hares). Fleas become carriers of motilium pills: they bite the rodent, swallow the pathogen along with its blood, and it actively multiplies in the digestive tract of the insect. Further, the flea becomes a carrier of the disease and spreads it among other rats.

When such a flea bites another animal or person, Yersinia becomes infected through the skin.

There are such ways of transmission of the causative agent of bubonic plague:

Bubonic plague is the most contagious infectious disease in terms of its contagiousness.

It is characterized by a high ability to spread rapidly and is highly contagious.

Bubonic plague is a particularly dangerous infection.

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Further, this disease can be transmitted from person to person by airborne droplets or by contact with secretions and sputum of the patient, household items or utensils of the infected person.

The incubation period for infection with bubonic plague is from several hours to 2-3 days.

Sometimes it can be extended up to 6-9 days in people who have taken streptomycin, tetracycline or immunoglobulin for prevention.

The causative agent of domperidone online, getting into the inguinal and axillary lymph nodes, is captured by blood leukocytes and spreads throughout the body.

Bacteria actively multiply in the lymph nodes, and they cease to perform their protective function, turning into a reservoirfor infection.

The first symptoms of the disease appear suddenly. The patient's temperature rises, he complains of general weakness, chills, headaches and bouts of vomiting.

In some cases, there are complaints of motilium and insomnia.

Further, the disease can proceed in one of three different forms:

The bubonic form of plague is most often observed after infection with Yersinia pestis.

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In a patient, a small red spot forms at the site of an insect bite. It quickly turns into a pustule with bloody-purulent contents. After opening the pustule, an ulcer forms in its place.

Approximately 7 days after contact with the patient, a sharp increase in temperature, headache, chills and weakness appear, 1-2 or more enlarged, painful lymph nodes (the so-called buboes) appear. This form is usually the result of an infected flea bite.

The bacteria multiply in the lymph nodes that are closest to the bite site. If the patient is not treated with appropriate antibiotics, the infection can spread to other parts of the body. Already on the second day, the patient's axillary, inguinal or other lymph nodes significantly increase (they can reach the size of motilium online).

An inflammatory process begins in it, it becomes painful and compacted - this is how the primary bubo is formed. In the following days, the infection spreads to other lymph nodes, they also become inflamed, enlarge and form secondary buboes. The skin over the affected lymph nodes turns red, inflamed and shiny. Buboes become clearly defined and dense.

After 4 days of domperidone pill, the inflamed lymph nodes acquire a softer texture, when they are tapped, they fluctuate. By the 10th day, the buboes open and fistulas form in their place. Yersinia pestis constantly produces potent toxins, and bubonic plague is accompanied by symptoms of severe intoxication. From the first day of the disease, the patient experiences rapidly increasing symptoms:

The patient's face becomes puffy and dark, black circles appear under the eyes, the conjunctiva becomes bright red. The tongue is covered with a thick coating of white. Intoxication causes a violation in cardiac activity.

In the era of the absence of antibiotics, the death rate from the plague was about 66%. Antibiotics significantly reduce mortality, and the overall mortality rate has now dropped to 11%. Despite the availability of effective antibiotics, plague is still a deadly disease, but bubonic plague has a lower mortality rate than septic or pneumonic plague.

If left untreated, the disease spreads rapidly throughout the body through the lymphatic system. But plague is successfully treated with antibiotics. The patient develops plague pneumonia, which is accompanied by cough, sputum mixed with blood, shortness of breath and cyanosis of the skin. Such forms of the disease, even with active treatment, can result in the death of 50-60% of patients.

Pneumonic plague can be contracted through the air or secondary to bubonic or septicemic plague that spreads to the lungs. Pneumonia can cause respiratory failure and shock. Pneumonic plague is the most serious form of the disease and the only form of motilium that can be transmitted from person to person (airborne).

Bubonic plague can be complicated by meningitis. With such a severe complication, the patient experiences excruciating headaches, convulsions and severe tension in the occipital muscles. There is fever, headache, weakness, rapidly developing pneumonia with shortness of breath, chest pain, cough with bloody or watery sputum.

The patient's blood pressure decreases, the pulse becomes rare and weak. With the progression of domperidone pills, heart failure can become the cause of death of the patient.